Story at-a-glance
- The primary approach to treating heart disease is to prescribe costly cholesterol-lowering statins (to the point over a trillion dollars have now been spent on them). Unfortunately, these highly toxic drugs have minuscule benefits (e.g., at best taking them for years extends your life by a few days)
- Statins are also one of the most frequent causes of pharmaceutical injuries (e.g., they are notorious for causing muscle, nerve, or liver damage and significant cognitive impairment). This is because statins work by blocking the body’s production of various essential nutrients
- Many of these failures can be explained by the fact there is very little evidence cholesterol actually causes heart disease. Rather, heart disease results from (cholesterol containing) atherosclerotic blood clots accumulating at the sites of past injuries to the blood vessels
- In this article, we will review the dangers of statins, the actual causes of heart disease, and how this knowledge can be integrated to develop a healthy approach to cardiovascular health
Medicine depends upon recurring sales to large markets. In turn, as comedian Jimmy Dore shows, the War against Cholesterol and the relentless promotion of statins is one of the most harmful things the medical industry has done to America:
The Statin Damage Crisis
Less severe reactions to a toxin are much more common than severe ones. Because of this, if you see a cluster of severe reactions, it indicates that far more, less severe reactions are occurring as well (which is how after learning a few people in my social circle had died suddenly from the COVID vaccines, I was able to correctly predict the almost unfathomable scale of the nonfatal COVID vaccine injuries that would hit America).
Likewise, if you see a large number of less severe reactions to a pharmaceutical, you can predict far more severe injuries are lurking in the background. In turn, available data shows statins injure roughly 1 in 5 recipients, most frequently with:
- Muscle damage (e.g., muscle pain and inflammation)1,2,3,4,5,6,7,8,9,10,11,12,13
- Fatigue14,15 (especially with exertion and exercise)16
- Diabetes17,18,19,20,21 (particularly in women)22,23,24
- Liver dysfunction and failure25,26
Likewise, even more severe injuries can also occur far too frequently such as:
- Psychiatric and neurologic issues such as depression, confusion, aggression, and memory loss27,28,29,30,31,32,33,34,35,36
- ALS-like conditions and other central motor disorders (e.g., Parkinson’s disease and cerebellar ataxia)37,38,39,40,41
Note: A more detailed list of statin side effects can be found here.
Sadly, effective marketing has made the medical profession remarkably resistant to acknowledging these frequent side effects of statins.
Statin Neurotoxicity
“Many statin victims say that abruptly, almost in the blink of an eye, they have become old people.” — Duane Graveline MD42
Dr. Graveline awoke to this issue after being started on a statin and then developing global amnesia (which is really scary) which disappeared once he stopped the statin.43
“When I suggested, on the basis of my 23 years as a family doctor, that perhaps my new medicine was the cause of my amnesia, the neurologist replied, almost scoffingly, that ‘Statins do not do that.’ He and many other physicians and pharmacists were adamant that this does not occur.”
Eventually, he was persuaded to try again.
“The year passed uneventfully and soon it was time for my next astronaut physical. NASA doctors joined the chorus I had come to expect from physicians and pharmacists during the preceding year, that statin drugs did not do this and at their bidding I reluctantly restarted Lipitor at one-half the previous dose.
Six weeks later I again descended into the black pit of amnesia, this time for twelve hours and with a retrograde loss of memory back to my high school days.”
Later he discovered:
“Perhaps stockholder loyalty explains why Pfizer management knew over a decade ago, during the first human use trial of Lipitor, of the cognitive impact to come when Lipitor was released to the public. Of their 2,503 patients tested with Lipitor, seven experienced transient global amnesia attacks and four others experienced other forms of severe memory disturbances, for a total of 11 cases out of 2,503 test patients.
This is a ratio of 4.4 cases of severe cognitive loss to result from every 1000 patients that took the drug. Not one word of warning of this was transmitted to the thousands of physicians who soon would be dispensing the drug.”
Because of this and other debilitating long-term complications (e.g., previously an extremely fit individual, he developed chronic exhaustion), Graveline became an expert on statin injuries and, in 2014, wrote “The Statin Damage Crisis,”44 a book which explains why these drugs are so dangerous.
Why Statins Are Harmful
Statins work by inhibiting an easy to target enzyme that is necessary for the production of cholesterol. Unfortunately, blocking that enzyme disrupts a variety of other vital physiologic processes. Let’s review what that enzyme does:
Since each of these enzymes is essential for the body, many problems can ensue.
Note: Some of the other affected biomolecules include nuclear factor-kappa B, tau proteins, and selenoproteins.
Cholesterol
Cholesterol has a few different essential functions in the body. These include:
• It is the precursor to many different hormones.
• The brain’s synapses (which, amongst other things, form memories) require cholesterol to function. Since cholesterol is too big to enter the brain, glial cells (support cells of the nervous system) synthesize it within the brain. Statins, unfortunately, inhibit glial cell production of cholesterol.
• Cognition is highly dependent upon cholesterol. For example, one study45 found that minor cognitive impairment could be detected in 100% of statin users if sufficiently sensitive testing was done (again illustrating how minor injuries are more common than severe ones). Likewise, a variety of more severe adverse effects on cognition are also observed:
“A patient’s rapid descent into dementia after a statin is started is much too often written off by their doctor as senile brain changes or beginning Alzheimer’s when the real culprit is their statin.”
[…]
Numerous studies have also found a significant association46 between low or lowered cholesterol levels and violence. Likewise, statin dementia is often characterized by aggression.
Finally, one of the most concerning side effects of statins is their tendency to cause ALS (a truly horrible rare disease — curiously also seen in association with the COVID-19 vaccines). This correlation is further supported by many reports of statin ALS improving once the statin is stopped.47
CoQ10
CoQ10 is an essential nutrient that both the mitochondria (which power the human body) and the stability of our cell walls depend upon. CoQ10 deficiency caused by statins is generally considered the most common cause of their side effects. This is really sad because those side effects could have been prevented if CoQ10 had been given with the statin. Unfortunately, this is unlikely ever to happen, as doing so would be equivalent to an admission statins could cause harm.
[…]
Some of the common energy-related side effects of statin CoQ10 deficiency include:
Mitochondrial damage | Lack of energy | Chronic fatigue syndrome |
Congestive heart failure and fluid retention | Shortness of breath | Gout |
Some of the side effects of statin CoQ10 deficiency weakening cell wall integrity include:
- Pancreatitis
- Rhabdomyolysis (rapid breakdown of skeletal muscle tissue)
- Tendon and ligament inflammation and rupture
- Hepatitis
[…]
Two of the most common consequences of statins CoQ10 depletion are myopathy (muscle pain, tiredness, weakness, and cramps) and peripheral neuropathy (numbness, tingling, or burning sensations, particularly in hands and feet).
Although myopathy is the most commonly reported side effect of statin usage, much of it (e.g., myositis) goes undetected. This is because the symptoms are often not accompanied by blood work showing muscle enzyme elevations and can only be detected by biopsies (which are rarely done relative to blood work).
One of the sadder things about statins is how aggressively they are pushed on diabetics (under the logic that since diabetics have an increased risk of heart disease, it is critical they take a statin to prevent them from having a heart attack). To highlight the absurdity of this, statins are well known to significantly increase your risk of diabetes (multiple studies have found this49), which I suspect is again due to them impairing mitochondrial function.
Similarly, peripheral neuropathy is a condition diabetics are well known to be at a high risk of. In one study, it was found that the risk of neuropathy (e.g., burning pain with tingling or numbness of the extremities) was increased by 14 to 26 times (depending on the type) for long-term users of statins.50 Likewise, other nerve issues, such as neurodegeneration, can be caused by statins.
[…]
Nuclear Factor-Kappa B
The small cardiovascular benefit from statins may come not from lowering cholesterol but from their anti-inflammatory properties, as they inhibit NF-kB, a key immune system component involved in inflammation (which causes heart disease). Statins also lower C-reactive protein, another inflammatory marker. However, by suppressing the immune system, they may reduce protection against infections and increase cancer risk.51
For example, a Japanese study found that 13.3% of lymphoid cancer patients had been on statins, compared to only 7.3% of non-cancer patients.52 In the PROSPER trial (a major statin study), while statins slightly reduced heart attack deaths, they were linked to a significant rise in cancer deaths, effectively neutralizing the cardiovascular benefit. Including nonfatal cancers, the difference between the control and statin groups grew each year.53
In addition to this, arguing that some of the benefit of statins “preventing heart attacks” is due to them causing a fatal cancer before you have time to have a natural heart attack, this situation is somewhat analogous to what was seen with the COVID vaccines (which also cause cancer).54
There, the “benefit” of the COVID vaccines preventing COVID was outweighed by them causing serious conditions such as heart attacks and strokes, but if one only focused on them preventing COVID (which many did), the vaccines could be portrayed as life-saving, even though they overall did the opposite.
[…]
Medical Mythologies
To sell a blockbuster drug, it’s often necessary to cement a cultural mythology behind it. For example, the antidepressant industry spent years convincing the public depression was due to a “chemical imbalance” (when in reality — raising serotonin causes suicidality), and as a result, despite the chemical imbalance theory having been disproven, over 13%55 of Americans take these dangerous, unnecessary and highly addictive drugs (a figure that sadly continues to rapidly rise).56
One of the cleverest campaigns I’ve seen within the medical industry is the widespread belief that heart disease is due to fat clogging the arteries much like they do for a drain pipe.
This marketing slogan in turn is remarkably persuasive as it is easy to understand (e.g., people without a medical background will feel confident repeating it to others), easy to visualize, and highly likely to elicit an immediate sense of disgust. But is it actually true?
The Clot Thickens
Malcolm Kendrick57 has extensively explored cholesterol, including a major mystery in cardiology — the fact that there is no common thread between the well-known risk factors for heart disease. For example, to calculate the risk of heart disease, England uses a calculator58 that combines the adjustable risks for heart disease (e.g., age) with the conditions most strongly associated with causing heart disease.
Age | Sex | Ethnicity |
Smoking | Diabetes | High BMI |
Postcode | Angina, or heart attack in first degree relative under the age of 60 | Atrial fibrillation |
Raised blood pressure | History of migraines | Chronic kidney disease |
Rheumatoid arthritis | Severe mental illness | Systemic lupus erythematosus (SLE) |
Variation in two blood pressure readings | On atypical antipsychotic medication | Using steroid tablets |
Total cholesterol/HDL ratio | Diagnosis of erectile dysfunction |
Likewise, in a 2017 study, the records of 378,256 English patients were analyzed by an AI system to determine what characteristics put them at the highest risk for a cardiovascular incident in the next 10 years. From that, they found that the ten greatest risk factors59 (in order) were:
- Chronic obstructive pulmonary disease
- Oral corticosteroid prescribed
- Age
- Severe mental illness
- Ethnicity South Asian
- Immunosuppressant prescribed
- Socio-economic status quintile 3
- Socio-economic status quintile 4
- Chronic kidney disease
- Socio-economic status quintile 2